Your arteries work around the clock, carrying oxygen-rich blood from your heart to tissues throughout your body. But over many years, deposits made of cholesterol, fat, calcium, and other substances can accumulate inside artery walls. This process is called atherosclerosis.Preventative health plans As plaque builds up, an artery may become narrower, reducing blood flow. In some situations, a blood clot can further restrict or completely block circulation. The challenging part? Atherosclerosis often causes no symptoms in its early stages. Discover more Heart health supplements Consult Online Doctors Cardiovascular disease prevention When symptoms do appear, they depend largely on which arteries are affected and how severely blood flow has been reduced.Explore Anatomy Models Here are 10 warning signs worth knowing. Leg Pain or Cramping While Walking One of the most characteristic symptoms of peripheral artery disease (PAD) is leg discomfort triggered by physical activity. It may feel like aching, heaviness, burning, fatigue, or cramping in your calf, thigh, buttock, ankle, or foot.

adminonSeptember 20, 2026